7 Causes of a Lump-in-Throat Sensation: Mucus Buildup, Cough

What Causes a Lump-in-Throat Sensation?

A persistent sensation of something being stuck in the throat, also known as globus sensation, is a common complaint that can significantly impact daily life. It can make swallowing uncomfortable and may be accompanied by coughing, throat pain, mucus buildup, nasal congestion, or even chest tightness.

Several underlying medical conditions and lifestyle factors can contribute to this sensation. Below are seven common causes and their associated symptoms.


1. Pharyngitis and Tonsillitis (Throat Inflammation)

Pharyngitis and tonsillitis are infections that cause throat inflammation and irritation, leading to a lump-in-throat sensation.

  • Caused by viral or bacterial infections such as the common cold or flu.
  • Symptoms include sore throat, coughing, mucus buildup, nasal congestion, fever, and chills.
  • Typically resolves within a week with rest and hydration.

2. Gastroesophageal Reflux Disease (GERD) & Laryngopharyngeal Reflux (LPR)

GERD and LPR occur when stomach acid flows back into the esophagus and throat, causing irritation and inflammation.

  • GERD symptoms: Heartburn, regurgitation, acid reflux, sour burping.
  • LPR symptoms: Hoarseness, throat clearing, chronic cough, and the sensation of mucus in the throat.
  • Lifestyle changes, such as avoiding overeating, late-night meals, fatty foods, alcohol, and carbonated drinks, can help manage symptoms.
  • Acid-suppressing medications may be prescribed for severe cases.

3. Postnasal Drip (Mucus Dripping Down the Throat)

Postnasal drip occurs when excess mucus from the nasal passages flows down the back of the throat, causing irritation.

  • Common causes: Allergies, sinus infections, chronic rhinitis.
  • Symptoms include constant throat clearing, coughing, and the feeling of thick mucus in the throat.
  • Drinking plenty of water and using saline nasal irrigation can help reduce symptoms.

4. Tonsil Stones (Tonsilloliths)

Tonsil stones are hardened deposits of food particles, bacteria, and debris that accumulate in the tonsil crevices.

  • Symptoms include a lump-in-throat sensation, throat irritation, ear pain, and bad breath.
  • Preventive measures include good oral hygiene, regular hydration, and gargling with salt water.

5. Pharyngeal Neuralgia (Globus Sensation Due to Nerve Sensitivity)

In some cases, a lump-in-throat sensation occurs even when no physical obstruction is present. This condition, known as pharyngeal neuralgia, is linked to stress and anxiety.

  • Psychological factors, such as nervousness, excessive worry, and stress, can heighten nerve sensitivity in the throat.
  • Treatment includes relaxation techniques, stress management, and cognitive behavioral therapy (CBT) if necessary.

6. Cancer (Throat or Esophageal Tumors)

Although rare, throat or esophageal cancer can cause a persistent lump-in-throat sensation.

  • Warning signs include difficulty swallowing, unexplained weight loss, vomiting, and coughing up blood.
  • If these symptoms occur, immediate medical evaluation is essential.

7. Dry Throat from Poor Lifestyle Habits

A dry throat caused by dehydration or environmental factors can lead to a persistent lump-in-throat sensation.

  • Common causes include low water intake, dry indoor air, air pollution, and prolonged exposure to harsh weather.
  • Maintaining hydration, using a humidifier, and avoiding irritants can help alleviate symptoms.

When to See a Doctor

If the sensation of a lump in the throat is persistent, painful, or accompanied by difficulty swallowing, fever, coughing up blood, or significant weight loss, a medical evaluation is necessary.

Doctors may perform:

  • Throat examination and laryngoscopy
  • Gastroscopy (to check for acid reflux-related issues)
  • CT scans if necessary

Since some causes of a lump-in-throat sensation can become chronic, early diagnosis and treatment are crucial to preventing long-term complications.